Advantage® II

Advantage® II
Advantage® II is a comprehensive flea prevention and treatment for dogs and cats that kills fleas through contact so they don’t have to bite your pet to die.
A brown and white dog sitting next to a grey and white fluffy kitten on a bed.
Why choose Advantage® II for your pet?
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Kills fleas, flea eggs and flea larvae
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Prevents flea re-infestation by breaking the flea life cycle for 30 days
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Easy-to-apply topical
How does it work?

Prevents and treats: Fleas, flea eggs and flea larvae in dogs and cats; lice in dogs

Works for: Puppies and dogs 7 weeks of age and older; kittens and cats 8 weeks of age and older; ferrets 10 weeks and older

Application type: Topical

Treatment frequency: Monthly

No prescription required

A man holding a ferret in his hand.
Advantage® II is also available for ferrets.

Once-a-month topical flea prevention and treatment for ferrets. For use only on ferrets 10 weeks and older and weighing 1 pound or more.

How does Advantage® II for Dogs work?

Advantage® II kills fleas through contact, so they don’t have to bite your dog to die. Learn how to apply this easy-to-use, odorless topical for dogs once per month to prevent fleas, flea larvae, flea eggs and chewing lice.

How does Advantage® II for Cats work?

Advantage® II kills fleas through contact, so they don’t have to bite your cat to die. Learn how to apply this easy-to-use, odorless topical for cats once per month to prevent fleas, flea larvae and flea eggs.

Ready to protect your pet from fleas?
Top questions about Advantage® II
Does Advantage® II for dogs expire?

There is no expiration date required on the packaging by the EPA for Advantage® II for dogs. The product should be kept in its original packaging and stored as directed on the label.

Can I bathe my dog after applying Advantage® II?

Yes. However, we suggest bathing your dog before applying Advantage® II. Just make sure your dog is dry before application. If you choose to bathe your dog in between treatments, we recommend use of a general grooming shampoo for pets. Keep in mind that more frequent bathing may keep the product from working the full 30 days.

Can my dog go swimming after I apply Advantage® II?

Yes! Your dog is free to take a dip after Advantage® II has been on for 24 hours. However, more frequent swimming may keep the product from working the full 30 days.

Can I apply Advantage® II for dogs on my cats?

No, do not use Advantage® II for dogs on cats. Please follow label directions for the application of our flea products.

How does Advantage® II for dogs work?

Advantage® II for dogs combines two active ingredients:

  • Imidacloprid attacks the flea's nervous system - paralyzing and ultimately killing it.
  • Pyriproxyfen is an insect growth regulator (IGR) that kills flea eggs and larvae.

This combination plays a crucial role in treating and preventing infestations, because:

  • In an existing infestation, you might only be aware of the adult fleas, which only represent around 5% of the full infestation and are found on the pet.
  • Immature flea life stages which live in the pet's environment consist of around 95% of the infestation and can be almost invisible to the naked eye.
What’s the difference between Advantage® II for dogs and oral flea products?

Advantage® II flea prevention is applied to your dog topically, spreading over the skin and hair. It kills fleas through contact, so fleas do not have to bite your dog to die. With oral flea medications, fleas have to bite your dog and ingest the medication before they are killed.

How long does Advantage® II for dogs last?

A single application of Advantage® II for dogs stops biting fleas for one month. However, if the dog has a severe infestation, retreatment within a month may be necessary. See product label for additional information.

How often can you use Advantage® II for dogs?

Use Advantage® II for dogs monthly, year-round to help keep your pet protected from fleas. Follow label directions for application.

How do I apply Advantage® II for dogs?

Applying Advantage® II for dogs flea control to your canine companion is easy and convenient. Before applying, check the weight range and minimum age on the package to choose the appropriate product for your dog.

How to apply Advantage® II for dogs:

  1. Remove the tube from packaging and open it by putting the cap on the other end and twisting to break the seal.
  2. Place the tip of the tube on the skin between your dog's shoulder blades and gently squeeze to expel the solution on their skin. The number of application spots depends on the size and weight of your dog.
  3. Lift the tube away from their skin, while maintaining pressure on the tube to make sure the product has all been squeezed out.

For more detailed instructions, watch our application video.

 

https://youtube.com/embed/lDS2xmvNOiI
How old does my dog have to be to use Advantage® II for dogs?

You can use Advantage® II for dogs on puppies and dogs 7 weeks of age and older.

How long does Advantage® II for dogs take to work?

Advantage® II for dogs kills fleas on dogs within 12 hours of application.

Can I touch my dog after applying Advantage® II for dogs?

Do not have contact or allow children to have contact with the area treated with Advantage® II for dogs until completely dry.

How do I store and dispose of Advantage® II?

Do not contaminate water, food or feed by storage or disposal of Advantage® II.

  • Storage: Store in a cool, dry place. Protect from freezing. Keep out of reach of children.
  • Disposal and Container Handling: Non-refillable container. If empty: Do not reuse this container. Place in trash or offer for recycling if available. If partly filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Can I bathe my cat after applying Advantage® II?

Yes. Advantage® II is waterproof after 24 hours. However, we suggest bathing your cat before applying Advantage® II. Just make sure your cat is dry before application. If you choose to bathe your cat in between treatments, we recommend use of a general grooming shampoo for pets. Keep in mind that more frequent bathing may keep the product from working the full 30 days.

Can I use Advantage® II for cats on dogs?

No, do not use Advantage® II for cats on dogs. Please follow label directions for the application of our flea products.

Can I split tubes of Advantage® II between my cats?

No, you cannot split tubes of Advantage® II for cats between multiple cats. To successfully prevent and control fleas, cats must be treated with their own dose of Advantage® II. Follow label directions for application.

How does Advantage® II for cats work?

Advantage® II for cats combines two active ingredients:

  • Imidacloprid attacks the flea’s nervous system — paralyzing and ultimately killing it.
  • Pyriproxyfen is an insect growth regulator (IGR) that kills flea eggs and larvae.

This combination plays a crucial role in treating and preventing infestations, because:

  • In an existing infestation, you might only be aware of the adult fleas, which only represent around 5% of the full infestation and are found on the pet.
  • Immature flea life stages which live in the pet’s environment consist of around 95% of the infestation and can be almost invisible to the naked eye.
What is the difference between Advantage® II for cats and oral flea products?

Advantage® II flea prevention is applied to your cat topically, spreading over the skin and hair. It kills fleas through contact, so fleas do not have to bite your cat to die. With oral flea medications, fleas have to bite your cat and ingest the medication before they are killed.

How do I apply Advantage® II for cats?

Applying Advantage® II for cats flea control to your feline friend is easy and convenient. Before applying, check the weight range and minimum age on the package to choose the appropriate product for your cat.

How to apply Advantage® II for cats:

  1. Remove the tube from packaging and open it by putting the cap on the other end and twisting to break the seal.
  2. Part the hair where the cat's head and neck come together (base of the skull) and place the tip of the tube on the skin, gently squeezing to expel the entire solution out onto the skin.
  3. Lift the tube away from their skin, while maintaining pressure on the tube to make sure the product has all been squeezed out.

For more detailed instructions, watch our application video.

https://www.youtube.com/embed/LaLhdaz1zao
How old does my cat have to be to use Advantage® II?

You can use Advantage® II for cats on kittens and cats 8 weeks of age and older.

Does Advantage® II for cats expire?

There is no expiration date required on the packaging by the EPA for Advantage® II for cats. We recommend the product should be kept in its original packaging and stored as directed on the label.

How long does Advantage® II for cats take to work?

Advantage® II for cats kills fleas within 12 hours of application.

Can I touch my cat after applying Advantage® II for cats?

Do not have contact or allow children to have contact with the area treated with Advantage® II for cats until completely dry.

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