Protect your pet with Advantage Multi® (imidacloprid + moxidectin)

German Shepherd and gray tabby cat relaxing together on bed
Protect your pet with Advantage Multi® (imidacloprid + moxidectin)
Advantage Multi® protects your pets from heartworms, fleas and intestinal worms* — with one simple, monthly dose.
Why choose Advantage Multi® for your pet?
An icon of group of parasites.
Help protect your pets from multiple parasites — like heartworms and intestinal worms* — with just one convenient monthly application.
An icon of a dead flea.
Kills fleas through contact, so they don’t have to bite to die.
An icon of a calendar with a check mark.
Heartworm protection that forgives if you forget. Even if you’re a few days late on this month’s dose, just treat immediately and resume your regular monthly schedule.
Find more reasons to love Advantage Multi®.

Protects against: 

  • In dogs: Heartworms, fleas, hookworms, roundworms, whipworms, sarcoptic mange
  • In cats: Fleas, ear mites, roundworms, hookworms, heartworms
  • In ferrets: Fleas, flea infestations, heartworms
     

Works for:

  • Dogs and puppies at least 7 weeks of age that weigh at least 3 pounds;
  • cats and kittens at least 9 weeks of age that weigh at least 2 pounds;
  • ferrets that weigh at least 2 pounds

Application type: Topical

Treatment frequency: Monthly

Prescription required

Man gently petting a boxer on the head
Life happens. Fortunately, there's Advantage Multi®.

Advantage Multi® for Dogs prevents future infection by killing newly acquired baby worms all day, every day throughout the month. This means after a single monthly dose, if you forget and go more than 30 days between heartworm prevention treatments, just treat immediately and resume your monthly schedule.

How to apply Advantage Multi®

It’s quick and simple.

Watch Advantage Multi® pet-owner testimonials.

See what some pet owners are saying about Advantage Multi®.

Learn more about the dangers of fleas.

Kills fleas within 12 hours of application. Reinfesting or new fleas are killed within two hours for the remainder of the month.
 

Experience the many layers of
Advantage Multi®.
Ready to protect your pet from heartworms, fleas and intestinal worms?* It’s available with a veterinarian’s prescription.
Top questions about Advantage Multi®
How often should I apply Advantage Multi® for Cats?

Use monthly (every 30 days), year-round, to kill fleas; treat flea infestations; treat and control ear mites, hookworms and roundworms; and prevent heartworm disease.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Cats to use by or on the order of a licensed veterinarian.

WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age or less than 2 lbs body weight. Do not use on ferrets less than 2 lbs body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application.

How do I apply Advantage Multi® for Cats?

Do not apply to irritated skin.

  1. Remove one dose applicator tube from the package.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of the cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. Part the hair on the back of the cat's neck at the base of the head, until the skin is visible. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin. Lift the tube away from skin before releasing pressure on the tube.

Do not get this product in the cat's mouth or eyes or allow the cat to lick the application site for 30 minutes. Treatment at the base of the head will minimize the opportunity for ingestion by grooming.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Cats to use by or on the order of a licensed veterinarian.

WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age or less than 2 lbs body weight. Do not use on ferrets less than 2 lbs body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application.

How old does my cat have to be to use Advantage Multi® for Cats?

Advantage Multi® for Cats can be used on cats at least 9 weeks old, weighing at least 2 pounds. The small cat size (5.1-9 lbs.) can be used for ferrets that weigh at least 2 pounds.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Cats to use by or on the order of a licensed veterinarian.

WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age or less than 2 lbs body weight. Do not use on ferrets less than 2 lbs body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application.

Does Advantage Multi® for Cats expire?

Advantage Multi® for Cats does have an expiration date that can be found on the bottom edge of the package. Advantage Multi® for Cats should not be used past its expiration date.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Cats to use by or on the order of a licensed veterinarian.

WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age or less than 2 lbs body weight. Do not use on ferrets less than 2 lbs body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application.

How does Advantage Multi® for Cats work to kill fleas?

Advantage Multi® for Cats is applied to the pet's skin. The active ingredient, imidacloprid, spreads over your cat's body to kill fleas through contact so they do not have to bite your cat to die.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Cats to use by or on the order of a licensed veterinarian.

WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age or less than 2 lbs body weight. Do not use on ferrets less than 2 lbs body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application.

What if I miss an Advantage Multi® for Cats heartworm treatment?

Life happens. If you forget or miss a dose, simply treat your cat immediately. Advantage Multi® for Cats is heartworm prevention that forgives if you forget.* It kills newly acquired heartworm larvae (baby worms) throughout the month to prevent further infection.

*After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Cats to use by or on the order of a licensed veterinarian.

WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age or less than 2 lbs body weight. Do not use on ferrets less than 2 lbs body weight.

PRECAUTIONS: Avoid oral ingestion.

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application.

Is Advantage Multi® for Dogs waterproof?

Advantage Multi® for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.1

Product Label

1. Freedom of Information Summary: NADA 141-251.

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How do I apply Advantage Multi® for Dogs?

Do not apply to irritated skin.

  1. Remove one dose applicator tube from the package.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of the cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog.

Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.

 

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How old does my dog have to be to use Advantage Multi® for Dogs?

Advantage Multi® for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

Does Advantage Multi® for Dogs expire?

Advantage Multi® for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi® for Dogs should not be used past its expiration date.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

When can I bathe my dog after using Advantage Multi® for Dogs?

We recommend bathing BEFORE applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How does Advantage Multi® for Dogs work to kill fleas?

Advantage Multi® for Dogs is applied to the pet’s skin. The active ingredient, imidacloprid, spreads over your dog’s body to kill fleas through contact so they don’t have to bite your dog to die.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

What if I miss an Advantage Multi® for Dogs heartworm treatment?

Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi® for Dogs is heartworm prevention that forgives if you forget.* It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month.

*After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How often can I use Advantage Multi® for Dogs?

Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

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