Advantage Multi® for Dogs (imidacloprid + moxidectin)
Advantage Multi® for Dogs (imidacloprid + moxidectin)

*Treats and controls roundworms, whipworms and hookworms in dogs.
Protection that’s worth the prescription




*Treats and controls roundworms, whipworms and hookworms in dogs.
Heartworm prevention for dogs that works all month long

Heartworm prevention for dogs that works all month long
Without prevention, heartworm disease can be deadly. Unlike oral heartworm preventives for dogs, the topical moxidectin in Advantage Multi® absorbs into the body and keeps killing worms all month long. Plus, Advantage Multi® forgives if you forget. So even if you’re a few days late applying that monthly dose, just treat immediately and resume your monthly schedule.
Watch how Advantage Multi® protects your dog from the dangers of heartworms >
Prevents five parasites in one easy dose

Prevents five parasites in one easy dose
Advantage Multi® protects against heartworms and intestinal worms at multiple stages, such as hookworms, roundworms and whipworms. It also prevents and treats flea infestations, killing fleas through contact so they don’t have to bite your dog to die. Advantage Multi® even treats and controls sarcoptic mange, a skin infection caused by parasitic mites that dogs can pick up from other dogs at doggy day care, dog parks and groomers.
†Based on label comparisons.
How to buy Advantage Multi® online

How to buy Advantage Multi® online
1. Visit your vet to get a prescription for Advantage Multi®.
2. Find Advantage Multi® online.
3. Add Advantage Multi® to your cart, and proceed to checkout.
4. Most retailers will request some details about your pet, along with your vet’s contact information to verify your prescription. (There will also be an option to mail in the prescription.)
5. A licensed pharmacist will fill your prescription and ship Advantage Multi® right to your door.
How to apply Advantage Multi® for Dogs




Top questions about Advantage Multi® for Dogs
Is Advantage Multi® for Dogs waterproof?
Advantage Multi® for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.1
Product Label
1. Freedom of Information Summary: NADA 141-251.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How do I apply Advantage Multi® for Dogs?
Do not apply to irritated skin.
- Remove one dose applicator tube from the package.
- While holding the tube in an upright position, remove the cap from the tube.
- Turn the cap over and push the other end of the cap onto the tip of the tube.
- Twist the cap to break the seal and then remove cap from the tube.
- The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog.
Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How old does my dog have to be to use Advantage Multi® for Dogs?
Advantage Multi® for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
Does Advantage Multi® for Dogs expire?
Advantage Multi® for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi® for Dogs should not be used past its expiration date.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
When can I bathe my dog after using Advantage Multi® for Dogs?
We recommend bathing BEFORE applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How does Advantage Multi® for Dogs work to kill fleas?
Advantage Multi® for Dogs is applied to the pet’s skin. The active ingredient, imidacloprid, spreads over your dog’s body to kill fleas through contact so they don’t have to bite your dog to die.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
What if I miss an Advantage Multi® for Dogs heartworm treatment?
Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi® for Dogs is heartworm prevention that forgives if you forget.* It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month.
*After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How often can I use Advantage Multi® for Dogs?
Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.