Advantage Multi® for Dogs (imidacloprid + moxidectin)

Advantage Multi® for Dogs (imidacloprid + moxidectin)

Your dog can be at risk from heartworms, intestinal worms* and fleas going to the dog park to hanging out in the backyard. Protect your dog from multiple parasites with Advantage Multi®, available with a veterinarian's prescription.
Advantage Multi for Dogs packaging

*Treats and controls roundworms, hookworms and whipworms in dogs.

Highly rated, thorough prevention against parasites

Why choose Advantage Multi® for Dogs?

An icon of group ofheartworm and intestinal worms.
Comprehensive protection against worms
Advantage Multi® protects your dog from parasites including heartworms and multiple intestinal worms.*
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No pills required
Simply apply to your dog’s back according to label directions once a month. No pills means less stress — for both of you.
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Fights flea infestations
Advantage Multi® kills fleas through contact so they don’t have to bite your dog to die.
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For puppies and adult dogs
Advantage Multi® protects multiple sizes and breeds of dogs throughout their lives — whether it’s a 7-week-old, 3-pound Beagle puppy or a 100-pound Great Dane.

Veterinarian-recommended prevention from multiple parasites

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Protects against: Heartworms, intestinal worms,* fleas, sarcoptic mange

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Works for: Dogs at least 7 weeks of age that weigh at least 3 lbs.

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Application type: Topical

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Treatment frequency: Monthly

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Prescription required

An icon of heartworms in a dog’s heart.
Prevents deadly heartworms all month long

Advantage Multi® prevents future infections by killing newly acquired baby worms all day, every day throughout the month. After a single monthly dose, if you forget and go more than 30 days between heartworm prevention treatments, just treat immediately and resume your monthly schedule.

An icon of a flea.
Prevents and treats flea infestations

Advantage Multi® kills fleas through contact. That means they don’t have to bite your dog to die. Re-infesting or new fleas are killed for the remainder of the month, even after your dog swims or bathes. 

An icon of intestinal worms in a dog’s intestines.
Kills multiple intestinal worms* at multiple stages

Most dogs will get at least one type of intestinal worm at some point in their lives, such as hookworms, roundworms or whipworms. Advantage Multi® helps you to deworm your dog by breaking down and debilitating worms at multiple life stages so your pup can expel them from their body.

A icon of a dog with flea allergy dermatitis on its back leg.
Treats and controls sarcoptic mange

Sarcoptic mange — a skin infection caused by parasitic mites — doesn’t affect only stray dogs. Our canine companions can also pick it up from other dogs at doggy daycares, dog parks and groomers. Advantage Multi® can help treat and control this highly contagious condition. 

See for yourself how Advantage Multi® for Dogs compares to other preventives.<sup>†</sup>

Based on label comparisons.

How to apply Advantage Multi® for Dogs

How to apply Advantage Multi for dogs: Step 1 turn the cap over
Step 1
Remove one dose applicator tube from the package. While holding the tube in an upright position, remove the cap from the tube.
How to apply Advantage Multi for dogs: Step 2 push the other end of cap onto the tip of tube
Step 2
Turn the cap over and push the other end of the cap onto the tip of the tube. Twist the cap to break the seal, and then remove the cap from the tube.
How to apply Advantage Multi for dogs: Step 3 locate visible skin area on dog's neck
Step 3
Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades.
How to apply Advantage Multi for dogs: Step 4 apply flea treatment on the area
Step 4
For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at three or four spots on the top of the backline from the base of the neck to the upper back.

Learn more about the dangers of heartworms — and how to help protect your dog

Advantage Multi® (imidacloprid + moxidectin) cartoon dog being examined by a vet

Ready to provide your dog with the multiple benefits of Advantage Multi®?

Top questions about Advantage Multi® for Dogs

Is Advantage Multi® for Dogs waterproof?

Advantage Multi® for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.1

Product Label

1. Freedom of Information Summary: NADA 141-251.

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How do I apply Advantage Multi® for Dogs?

Do not apply to irritated skin.

  1. Remove one dose applicator tube from the package.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of the cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog.

Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.

 

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How old does my dog have to be to use Advantage Multi® for Dogs?

Advantage Multi® for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

Does Advantage Multi® for Dogs expire?

Advantage Multi® for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi® for Dogs should not be used past its expiration date.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

When can I bathe my dog after using Advantage Multi® for Dogs?

We recommend bathing BEFORE applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How does Advantage Multi® for Dogs work to kill fleas?

Advantage Multi® for Dogs is applied to the pet’s skin. The active ingredient, imidacloprid, spreads over your dog’s body to kill fleas through contact so they don’t have to bite your dog to die.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

What if I miss an Advantage Multi® for Dogs heartworm treatment?

Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi® for Dogs is heartworm prevention that forgives if you forget.* It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month.

*After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How often can I use Advantage Multi® for Dogs?

Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

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