Advantage Multi® (imidacloprid + moxidectin) for Dogs

Advantage Multi® (imidacloprid + moxidectin) for Dogs
Advantage Multi® for Dogs helps protect your canine pal from more than just heartworm disease. This broad-spectrum prevention also protects from fleas, and treats and controls intestinal worms and sarcoptic mange.
Advantage Multi for Dogs packaging
Available with a veterinarian’s prescription
Why choose Advantage Multi® for your dog?
An icon of group of parasites.
Helps protect your dog from heartworms, fleas, intestinal worms and sarcoptic mange — all in just one easy-to-use monthly dose
An icon of a calendar with a check mark.
Heartworm protection that forgives if you forget. Even if you’re a few days late on this month’s dose, just treat immediately and resume your regular monthly schedule.
An icon of a dead flea.
Kills fleas through contact, so they don’t have to bite your dog to die

Treats and controls roundworms, hookworms and whipworms in dogs and roundworms and hookworms in cats.

Learn more about the dangers of heartworms — and how to help protect your dog
How does it work?

Protects against: Heartworms, microfilaria, fleas, hookworms, roundworms, whipworms, sarcoptic mange

Works for: Dogs and puppies at least 7 weeks of age that weigh at least 3 lbs.

Application type: Topical

Treatment frequency: Monthly

Veterinary prescription required

Man gently petting a boxer on the head
Life happens. Fortunately, there’s Advantage Multi® for Dogs.

Advantage Multi® for Dogs prevents future infection by killing newly acquired baby worms all day, every day throughout the month. That means after a single monthly dose, if you forget and go more than 30 days between heartworm prevention treatments, just treat immediately and resume your monthly schedule.

How to apply Advantage Multi® for Dogs

It’s quick and simple.

Ready to provide your dog with the multilayered benefits of Advantage Multi®?
See for yourself how Advantage Multi® for Dogs compares to other preventives.*
  Advantage Multi® logo with ingredients (imidacloprid + moxidectin) ProHeart® 12 logo** Simparica Trio logo trifexis Sentinel® Spectrum logo Interceptor® Plus logo Revolution® logo Heartgard® Plus logo
HEARTWORMS YES YES YES YES YES YES YES YES
MICROFILARIA YES NO NO NO NO NO NO NO
FLEAS YES NO YES YES YES NO YES NO
SARCOPTIC MANGE YES NO NO NO NO NO YES NO
EAR MITES NO NO NO NO NO NO YES NO
ROUNDWORMS                
T. canis adults YES NO YES YES YES YES NO YES
T. canis immature adults NO NO YES NO NO NO NO NO
T. canis L4 YES NO NO NO NO NO NO NO
T. leonina YES NO YES YES YES YES NO YES
HOOKWORMS                
A. caninum adults YES YES YES YES YES YES NO YES
A. caninum immature adults YES NO NO NO NO NO NO NO
A. caninum L4 YES YES NO NO NO NO NO NO
U. stenocephala adults YES YES YES NO NO NO NO YES
U. stenocephala immature adults YES NO NO NO NO NO NO NO
U. stenocephala L4 YES YES NO NO NO NO NO NO
A. braziliense NO NO NO NO NO NO NO YES
WHIPWORMS YES NO NO YES YES YES NO NO
TAPEWORMS NO NO NO NO YES YES NO NO
TICKS NO NO YES NO NO NO YES NO

*Based on label indications: parasites and life stages.

**ProHeart® 6 and 12 is indicated for the treatment of existing larval and adult hookworm (Anclyostoma caninum and Uncinaria stenocephala) infections.

 

How to apply Advantage Multi® for Dogs
How to apply Advantage Multi for dogs: Step 1 turn the cap over
Step 1
Remove one dose applicator tube from the package. While holding the tube in an upright position, remove the cap from the tube.
How to apply Advantage Multi for dogs: Step 2 push the other end of cap onto the tip of tube
Step 2
Turn the cap over and push the other end of the cap onto the tip of the tube. Twist the cap to break the seal, and then remove the cap from the tube.
How to apply Advantage Multi for dogs: Step 3 locate visible skin area on dog's neck
Step 3
Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades.
How to apply Advantage Multi for dogs: Step 4 apply flea treatment on the area
Step 4
For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at three or four spots on the top of the backline from the base of the neck to the upper back. Please see product label for complete application instructions.
Top questions about Advantage Multi® for Dogs
Is Advantage Multi® for Dogs waterproof?

Advantage Multi® for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.1

Product Label

1. Freedom of Information Summary: NADA 141-251.

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How do I apply Advantage Multi® for Dogs?

Do not apply to irritated skin.

  1. Remove one dose applicator tube from the package.
  2. While holding the tube in an upright position, remove the cap from the tube.
  3. Turn the cap over and push the other end of the cap onto the tip of the tube.
  4. Twist the cap to break the seal and then remove cap from the tube.
  5. The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog.

Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.

 

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How old does my dog have to be to use Advantage Multi® for Dogs?

Advantage Multi® for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

Does Advantage Multi® for Dogs expire?

Advantage Multi® for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi® for Dogs should not be used past its expiration date.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

When can I bathe my dog after using Advantage Multi® for Dogs?

We recommend bathing BEFORE applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. 

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How does Advantage Multi® for Dogs work to kill fleas?

Advantage Multi® for Dogs is applied to the pet’s skin. The active ingredient, imidacloprid, spreads over your dog’s body to kill fleas through contact so they don’t have to bite your dog to die.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

What if I miss an Advantage Multi® for Dogs heartworm treatment?

Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi® for Dogs is heartworm prevention that forgives if you forget.* It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month.

*After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

How often can I use Advantage Multi® for Dogs?

Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.

Product Label

CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.

WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)

CONTRAINDICATIONS: Do not use this product on cats.

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