Advantage Multi® (imidacloprid + moxidectin) for Dogs
Advantage Multi® (imidacloprid + moxidectin) for Dogs
Why choose Advantage Multi® for your dog?
†Treats and controls roundworms, hookworms and whipworms in dogs and roundworms and hookworms in cats.
Learn more about the dangers of heartworms — and how to help protect your dog
How does it work?
Protects against: Heartworms, microfilaria, fleas, hookworms, roundworms, whipworms, sarcoptic mange
Works for: Dogs and puppies at least 7 weeks of age that weigh at least 3 lbs.
Application type: Topical
Treatment frequency: Monthly
Veterinary prescription required
Advantage Multi® for Dogs prevents future infection by killing newly acquired baby worms all day, every day throughout the month. That means after a single monthly dose, if you forget and go more than 30 days between heartworm prevention treatments, just treat immediately and resume your monthly schedule.
It’s quick and simple.
See for yourself how Advantage Multi® for Dogs compares to other preventives.*
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| HEARTWORMS | YES | YES | YES | YES | YES | YES | YES | YES | |
| MICROFILARIA | YES | NO | NO | NO | NO | NO | NO | NO | |
| FLEAS | YES | NO | YES | YES | YES | NO | YES | NO | |
| SARCOPTIC MANGE | YES | NO | NO | NO | NO | NO | YES | NO | |
| EAR MITES | NO | NO | NO | NO | NO | NO | YES | NO | |
| ROUNDWORMS | |||||||||
| T. canis adults | YES | NO | YES | YES | YES | YES | NO | YES | |
| T. canis immature adults | NO | NO | YES | NO | NO | NO | NO | NO | |
| T. canis L4 | YES | NO | NO | NO | NO | NO | NO | NO | |
| T. leonina | YES | NO | YES | YES | YES | YES | NO | YES | |
| HOOKWORMS | |||||||||
| A. caninum adults | YES | YES | YES | YES | YES | YES | NO | YES | |
| A. caninum immature adults | YES | NO | NO | NO | NO | NO | NO | NO | |
| A. caninum L4 | YES | YES | NO | NO | NO | NO | NO | NO | |
| U. stenocephala adults | YES | YES | YES | NO | NO | NO | NO | YES | |
| U. stenocephala immature adults | YES | NO | NO | NO | NO | NO | NO | NO | |
| U. stenocephala L4 | YES | YES | NO | NO | NO | NO | NO | NO | |
| A. braziliense | NO | NO | NO | NO | NO | NO | NO | YES | |
| WHIPWORMS | YES | NO | NO | YES | YES | YES | NO | NO | |
| TAPEWORMS | NO | NO | NO | NO | YES | YES | NO | NO | |
| TICKS | NO | NO | YES | NO | NO | NO | YES | NO |
*Based on label indications: parasites and life stages.
**ProHeart® 6 and 12 is indicated for the treatment of existing larval and adult hookworm (Anclyostoma caninum and Uncinaria stenocephala) infections.
How to apply Advantage Multi® for Dogs
Top questions about Advantage Multi® for Dogs
Is Advantage Multi® for Dogs waterproof?
Advantage Multi® for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.1
Product Label
1. Freedom of Information Summary: NADA 141-251.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How do I apply Advantage Multi® for Dogs?
Do not apply to irritated skin.
- Remove one dose applicator tube from the package.
- While holding the tube in an upright position, remove the cap from the tube.
- Turn the cap over and push the other end of the cap onto the tip of the tube.
- Twist the cap to break the seal and then remove cap from the tube.
- The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible. For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog.
Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How old does my dog have to be to use Advantage Multi® for Dogs?
Advantage Multi® for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
Does Advantage Multi® for Dogs expire?
Advantage Multi® for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi® for Dogs should not be used past its expiration date.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
When can I bathe my dog after using Advantage Multi® for Dogs?
We recommend bathing BEFORE applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi® for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How does Advantage Multi® for Dogs work to kill fleas?
Advantage Multi® for Dogs is applied to the pet’s skin. The active ingredient, imidacloprid, spreads over your dog’s body to kill fleas through contact so they don’t have to bite your dog to die.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
What if I miss an Advantage Multi® for Dogs heartworm treatment?
Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi® for Dogs is heartworm prevention that forgives if you forget.* It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month.
*After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
How often can I use Advantage Multi® for Dogs?
Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.
CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian.
WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. For the first 30 minutes after application ensure that dogs cannot lick the product from application sites on themselves or other treated animals. Children should not come in contact with the application sites for two (2) hours after application. (See Contraindications, Warnings, Human Warnings, and Adverse Reactions, for more information.)
CONTRAINDICATIONS: Do not use this product on cats.
